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MHRA on GOV.UKOct 15, 2026

Guidance: Antidepressants: use and safety

MHRA updated its antidepressant use and safety guidance for healthcare professionals to reflect its review of patient risk communication. The update concerns information on suicidal thoughts and behaviours and sexual dysfunction that persists after treatment stops.

Why it matters: MHRA's guidance covers safety topics relevant to clinical research discussions, including withdrawal, pregnancy and medicine interactions.

Safety and recallsRegulations and guidanceAI summary
Read at MHRA

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